Background: Although injury is the leading cause of cardiac arrests in chil
dren older than 1 year, few studies have examined the survival and function
al outcome of cardiopulmonary resuscitation (CPR) in pediatric trauma patie
nts.
Methods: A historical cohort of 957 trauma patients younger than 15 years w
ho received CPR at the scene of injury or at the admitting hospital was con
structed on the basis of the National Pediatric Trauma Registry. The rate o
f survival to discharge and factors related to survival were examined. Func
tional impairments were documented for surviving patients.
Results: The overall survival rate was 23.5%, With adjustment for the Injur
y Severity Score, the risk of fatality after CPR increased for children wit
h systolic blood pressure below 60 mm Hg at admission (odds ratio [OR] 24.5
, 95% confidence interval [CI] 8.6-69.3), for those who were comatose at ad
mission (OR, 4.7; 95% CI, 1.9-11.6), for those with penetrating injury (OR,
4.4; 95% CI, 1.5-13.3), and for those with CPR initiated at the hospital (
OR, 2.4; 95% CI, 1.5-3.9), Surviving patients stayed in hospitals for an av
erage of 24.3 days; at discharge, 64% had at least one impairment in the fu
nctional activities of daily living.
Conclusions: Survival outcome of CPR in pediatric trauma patients appears t
o be comparable to that reported in adults of mixed arrest causes. Future r
esearch needs to identify factors underlying the excess mortality associate
d with penetrating trauma.