DIFFERENTIAL SCANNING CALORIMETRY AS A TOOL TO STUDY PROTEIN LIGAND INTERACTIONS

Authors
BARONE G CATANZANO F DELVECCHIO P GIANCOLA C
Citation
G. Barone et al., DIFFERENTIAL SCANNING CALORIMETRY AS A TOOL TO STUDY PROTEIN LIGAND INTERACTIONS, Pure and applied chemistry, 67(11), 1995, pp. 1867-1872
Citations number
36
Categorie Soggetti
Chemistry
Journal title
Pure and applied chemistry → ACNP
ISSN journal
00334545
Volume
67
Issue
11
Year of publication
1995
Pages
1867 - 1872
Database
ISI
SICI code
0033-4545(1995)67:11<1867:DSCAAT>2.0.ZU;2-Y
Abstract
Differential scanning calorimetry can be used as an interesting tool t o study protein-ligand interactions, with the aid of suitable thermody namic models. This review analyzes and discusses results recently obta ined in our laboratory with regard to the binding equilibrium of 2' an d 3' cytidine monophosphate to RNAase A, the interaction of S-peptide with S-protein, the binding of D-glucose to yeast hexokinase and the t hermal stability of respective complexes.