Comparison of two models for pattern generation based on synaptic depression

Previously, we developed two similar 3-variable models to explain the patte rn of spontaneous rhythmic activity generated by the spinal cord of chick e mbryo. The models differ in the implementation of a slow depression variabl e, but each produces patterns of activity that qualitatively resemble exper imental recordings. For both models, the ratio inter-episode interval/episo de duration (i/d ratio) was too small compared to experiments. The introduc tion of a parameter representing the connectivity of the network has differ ent effects on each model, therefore allowing them to be distinguished expe rimentally. Also, the model that seems to better satisfy experimental const raints is able to generate a large i/d ratio. (C) 1999 Elsevier Science B.V . All rights reserved.