First syntheses of the pyrroloketopiperazine marine natural products (+/-)-longamide, (+/-)-longamide B, (+/-)-longamide B methyl ester and (+/-)-hanishin
Mg. Banwell et al., First syntheses of the pyrroloketopiperazine marine natural products (+/-)-longamide, (+/-)-longamide B, (+/-)-longamide B methyl ester and (+/-)-hanishin, NEW J CHEM, 23(7), 1999, pp. 687-690
The marine natural products (+/-)-longamide (1), (+/-)-longamide B methyl e
ster (2), (+/-)-longamide B (3) and (+/-)-hanishin (4), each of which embod
ies a pyrroloketopiperazine core, have been synthesised in a concise fashio
n from pyrrole.