S. Aksit et al., Rubella seroprevalence in an unvaccinated population in Izmir: recommendations for rubella vaccination in Turkey, PEDIAT INF, 18(7), 1999, pp. 577-580
Background. The European Advisory GI roup on the Expanded Program on Immuni
zation of WHO has recommended that by 2010 or earlier congenital rubella sh
ould be well-controlled or eliminated in all countries in Europe. Debate on
the introduction of rubella vaccine into national immunization schedules c
ontinues to occur, and data on rubella and congenital rubella syndrome in T
urkey are insufficient.
Objective, To determine age-specific rubella seroprevalence in the 1- to 29
-year-old unvaccinated population in Izmir, Turkey.
Methods, A total of 600 unvaccinated persons 1 to 29 years old were selecte
d for the study with cluster sampling in Izmir, Turkey. The information on
sociodemographic characteristics and disease history was gathered for each
participant, and in 580 of them rubella-specific IgG antibodies were assaye
d quantitatively by the micro-enzyme immunoassay,
Results. Of the 580 participants tested for rubella antibodies, 135 (23.3%)
were seronegative, The proportions of susceptible individuals were 61.7, 2
9.5, 12.4, 10.3 and 8.4% in the age groups of 1 to 4, 5 to 9, 10 to 14, 15
to 19 and 20 to 29 years, respectively. Of the young women 15 to 19 years o
f age, 13.5% were susceptible to rubella infection,
Conclusions. Because a substantial proportion of women in their childbearin
g years are susceptible to rubella, immunization efforts should be directed
at infants or prepubertal children.