We investigate the influence of biquadratic exchange interactions on the lo
w-lying excitations of a S = 1/2 ladder using perturbation theory, numerica
l diagonalization of finite systems, and exact results for ladders with mat
rix product ground states. We consider in particular the combination of biq
uadratic exchange interactions corresponding to ring exchange on the basic
ladder plaquette. We find that a moderate amount of ring exchange reduces t
he spin gap substantially and makes equal bilinear exchange on legs and run
gs consistent with experimentally observed spectra. [S0163-1829(99)05425-9]
.