Non-antibiotic therapy of bovine mastitis is gaining importance in both are
a's field and science. This is chiefly due to unsatisfactory results of ant
ibiotic therapy and the goal to avoid antibiotic residues in food. Consider
ing effectiveness and disposability, frequent milking of mastitis cows and
the application of oxytocin and secretolytics can be recommended. Vaccines
of E. coli and S. aureus as well as the antimicrobial proteins nisin and ly
sostaphin which have proven their effectiveness are legally no yet admitted
in Germany, though this will surely change within the coming years. Furthe
r vaccines of mastitis-inducing pathogens and cytokines are still in develo
pment, thus a definite evaluation is not yet possible. Both, the contradict
ory information on homeopathy and the obtained results of physical therapy
tack the proof of effectiveness and can therefore not be recommended as mas
titis therapeutic agents.