Affinity chromatography was introduced 30 years ago and is the most powerfu
l tool for purification of biologically active molecules. Affinity chromato
graphy has also had a major impact and virtually revolutionized the entire
field of modem biology, molecular biology, biochemistry, medicine and biote
chnology. The development of affinity chromatography has led to many other
studies and applications in which the concept of molecular recognition and
biorecognition is used. (C) 1999 Elsevier Science B.V. All rights reserved.