The paper reviews key ideas in the firm capabilities literature and shows h
ow they can be usefully extended to develop a conception of collective lear
ning among regionally clustered enterprises. The paper also explores the re
lationship between codifiable and tacit knowledge in the innovation process
, and investigates the claim that tacit knowledge, because it is difficult
to transfer in the absence of labour mobility, may constitute a basis for s
ustained regional competitive advantage. The closing section uses case stud
y material based on Minneapolis and Cambridge to illustrate the importance
for innovation of a regional capability for combining and integrating diver
se knowledge, and of the sources of such capabilities as pre-conditions for
successful high technology regions.