Asymmetrical induction in the synthesis of ferrocenyl-substituted bicyclicpyrazolines. E,Z-isomerization of the ferrocenylmethylidene fragment

Asymmetrical induction in the synthesis of bicyclic ferrocenyl-substituted pyrazolines was studied. High diastereoselectivity of induction of the chir al center by the chiral center of the 1,2 type was observed. The cis diaste reomer of 2-acetyt-3-ferrocenyl-7-ferrocenylmethylidene-2,3,3a,4,5,6,7-hept ahydroindazole was studied by X-ray diffraction analysis. The E,Z-configura tional isomerism of the ferrocenylmethylene fragment of pyrazolines in an a cidic medium is described.