Wernicke's encephalopathy in alcoholics

Wernicke's encephalopathy should be suspected in all cases of confusion in nutritionally deprived individuals especially alcoholics. Both complete and limited forms of the disease can occur. Unfamiliarity with the condition, incomplete clinical picture and superimposed withdrawals may cause confusio n and delay in diagnosis. Gait abnormality is the most outstanding feature of the disease. Ocular abnormalities may have prognostic significance. Resp onse to intramuscular thiamine is good.