We report on 8 Norwegian travellers to Southern Africa with African tick-bi
te fever (ATBF), a recently described spotted fever group rickettsiosis. Al
l patients had acute flu-like symptoms and developed 1 or multiple inoculat
ion eschars. The patients were treated with either doxycycline or ciproflox
acin, and all recovered. The diagnosis of ATBF was confirmed by the detecti
on of specific IgM antibodies to Rickettsia africae by microimmunofluorosce
nce in convalescent-phase serum samples.