A versatile new synthesis of 3-aryl-3H-benzofuran-2-ones

Authors
Nesvadba, P Bugnon, L Dubs, P Evans, S
Citation
P. Nesvadba et al., A versatile new synthesis of 3-aryl-3H-benzofuran-2-ones, SYNLETT, 1999, pp. 863-864
Citations number
10
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNLETT
ISSN journal
09365214 → ACNP
Year of publication
1999
Pages
863 - 864
Database
ISI
SICI code
0936-5214(1999):<863:AVNSO3>2.0.ZU;2-U
Abstract
Aromatic or heteroaromatic hydrocarbons are easily alkylated with 3-hydroxy -3H-benzofuran-2-ones under Friedel-Crafts or acid catalysis to afford 3-ar yl-3H-benzofuran-2-ones in good yield. Access to the starting 3-hydroxy-3H- benzofuran-2-ones is easily achievable by reaction of suitably substituted phenols with glyoxylic acid.