4-diazocyclohexa-2,5-dienone derivatives as photoaffinity labels for proteins: Scope and limitations

Authors
Colas, C Grutter, T Goeldner, M
Citation
C. Colas et al., 4-diazocyclohexa-2,5-dienone derivatives as photoaffinity labels for proteins: Scope and limitations, SYNLETT, 1999, pp. 889-892
Citations number
19
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNLETT
ISSN journal
09365214 → ACNP
Year of publication
1999
Pages
889 - 892
Database
ISI
SICI code
0936-5214(1999):<889:4DAPLF>2.0.ZU;2-U
Abstract
4-Diazocyclohexa-2,5-dienone derivatives are presented as photosensitive re agents generating reactive carbene species which allow efficient photo-coup ling reactions with proteins. However, during such coupling reactions, the photogenerated hydroquinones can initiate undesired redox side reactions.