Prognosis of tonsillectomy in patients with IgA nephropathy

IgA nephropathy (IgAN) is a type of chronic glomerulonephritis characterize d by ISA deposits mainly in the mesangial area. It does not have so favoura ble a prognosis as was initially thought. This nephropathy is one of the di seases affected by tonsillar focal infections, and there have been patients in whom tonsillectomy has been effective. In this study, 24 patients with IgAN were followed for more than 2 years after tonsillectomy and studied cl inicopathologically. Remission of proteinuria was observed in 41.7% of the patients 6 months after surgery and in 50.0% 2 years after surgery. At 2 ye ars after surgery, patients with minor and focal segmental renal lesions Sh owed a significantly higher rate of remission of proteinuria than patients with diffuse renal lesions. There was no statistically significant differen ce between positive and negative patients in the rate of remission of prote inuria based on any parameter of the tonsillar provocation test at any time after surgery.