Adolescent reproductive events and subsequent breast cancer risk

Objectives rs. This study investigated the relationship between reproductiv e events during adolescence and subsequent breast cancer risk. Methods. Logistic regression models used self-reported data from 862 case p atients slid 790 controls in the Carolina Breast Cancer Study. Results. Miscarriage induced abortion, and full-term pregnancy before 20 ye ars of age were not associated with breast cancer. Among premenopausal wome n breast-feeding before 20 years of age was inversely associated with disea se. Oral contraceptive rase before 18 years of age was positively associate d with disease risk among African American women only. Conclusions. Pregnancy during adolescence does not appear to influence brea st cancer risk, but breast-feeding may. A possible increased breast cancer risk; among Africas American women who used oral contraceptives as adolesce nts warrants further study.