A patient with a large anterior mediastinal mass with minimal respiratory s
ymptoms presented for a diagnostic biopsy of the mass. A pre-operative thor
acic computed tomographic scan demonstrated narrowing of the distal trachea
, and right and left main stem bronchi. An awake intubation was done. Thiop
entone and muscle relaxant were given and surgery commenced. High airway pr
essure developed and ventilation became difficult, although oxygenation rem
ained satisfactory throughout. Anaesthetic implications are discussed. We r
ecommend that patients with more than 50% obstruction of the airway at the
level of the lower trachea and main bronchi have their femoral vessels cann
ulated in readiness for cardiopulmonary bypass.