Quantification of phenolphthalein in cosmetic products

Authors
Gagliardi, L De Orsi, D Multari, G Cavazzutti, G Tonelli, D
Citation
L. Gagliardi et al., Quantification of phenolphthalein in cosmetic products, ANALUSIS, 27(2), 1999, pp. 163-165
Citations number
10
Categorie Soggetti
Spectroscopy /Instrumentation/Analytical Sciences
Journal title
ANALUSIS
ISSN journal
03654877 → ACNP
Volume
27
Issue
2
Year of publication
1999
Pages
163 - 165
Database
ISI
SICI code
0365-4877(199903)27:2<163:QOPICP>2.0.ZU;2-K
Abstract
A simple method for the quantification of phenolphthalein in cosmetic formu lations is described. The sample, acidified with acetic acid, is extracted with methanol and analysed by reversed-phase HPLC on a column packed with 5 mu m SelectB RP-8. The initial mobile phase is acetonitrile-aqueous 0.1 M acetic acid (10:90), then a linear gradient up to 90% acetonitrile is appli ed in 30 min. The limit of determination is 1 ng injected when detection is performed at 230 nm.