Determination of permethrin in indoor air by liquid chromatography with enzyme linked immunosorbent assay

Synthetic pyrethroids Like permethrin are an important class of insecticide s and have been used as active ingredients against various garden or househ old pests, e.g. houseflies, mosquitoes and fleas for indoor-extermination. Thus, pyrethroids could have a high persistence in indoor areas which could lead to permanent health hazards to occupants of contaminated houses. The objective of this study was to develop a method for the determination o f permethrin in indoor air on the basis of a quantitative enzyme linked imm unosorbent assay (ELISA). In air, permethrin is bound to particles, due to its physical and chemical properties. For quantitative permethrin measurements for the optimisation of the sampli ng and extraction method, as well as, for the verification of the ELISA res ults, a liquid chromatography method was developed. (C) 1999 Elsevier Scien ce B.V. All rights reserved.