Essentials in biliopancreatic staging: A decision analysis

Two possible strategies for diagnosis and staging of patients with suspecte d biliopancreatic cancer and obstructive jaundice were tested in a decision analysis. One strategy was called 'surgical' strategy and consisted of only Ultrasono graphy and (spiral) CT scan and exploratory laparotomy in all patients with out irresectable disease or distant metastases according to this work-up. T he other strategy was called 'nonsurgical' strategy and consisted of the ab ove strategy, but also included ERCP and endoscopic internal drainage (sten t) and diagnostic laparoscopy and laparoscopic ultrasound. In the decision analysis incidences of the outcomes after the two strategie s were estimated based on the literature and our own experience, and a util ity (0-1) was attributed to each separate outcome, according to the expecte d duality of life as judged by the team. Total utility of each strategy was calculated. It could be concluded that a non-surgical strategy would lead to a somewhat higher total utility in case the yield (i.e, prevention of un necessary laparotomies) could be high and supposed that a beneficial effect of pre-operative internal biliary drainage was present. In case of low yie ld of diagnostic laparoscopy the superiority of the 'non-surgical' strategy is doubtful.