Despite the recognition of lead poisoning in children as a major public hea
lth problem in France since the 1980's, the setting-up of systematic detect
ion of lead poisoning at a national level has not yet been done. The main s
ource of intoxication in children is in paintings containing ceruse in hous
ing built before 1948. Moderate chronic poisoning, although leading to irre
versible lesions, particularly of the central nervous system, remains usual
ly unnoticed. The biological diagnosis is mainly based upon blood lead leve
l, completed by the protoporphyrine-zinc level. Large scale identification
of dangerous housing and the control of rehabilitation are the only means a
vailable to decrease the incidence of lead poisoning. Targeted screening is
difficult because it concerns children excluded from classical health care
systems. Prevention and long-term treatment requires elimination of the so
urce of lead intoxication after an environmental inquiry. This raises the p
roblems of rehousing and follow-up of intoxicated children. (C) 1999 Elsevi
er, Paris.