Protein transport along the secretory pathway is supported by a noria of ve
sicles that bud and fuse, load and unload their cargo from one compartment
into the other. However, despite this constant flow-through of proteins and
lipids the various compartments of the secretory pathway are able to maint
ain their own specific composition. Here, we discuss recent insights into m
echanisms of protein retention and localization that are necessary for the
maintenance of endoplasmic reticulum (ER)- and Golgi-associated typical fun
ctions such as protein folding and glycosylation in plant cells. (C) Societ
e francaise de biochimie et biologie moleculaire / Elsevier, Paris.