Paraneoplastic cicatricial pemphigoid

We report a 39-year-old woman with antiepiligrin cicatricial pemphigoid (CP ) in association with non-small cell carcinoma of the lung. At presentation , mucosal lesions showed minimal response to combined systemic immunosuppre ssive agents. Following the diagnosis of non-small cell lung carcinoma and subsequent treatment with gemcitabine (a second-line chemotherapeutic agent ), a significant reduction in both tumour mass and mucosal blistering was o bserved. Metastatic disease was subsequently associated with recurrent oral erosions. We believe this patient represents the first reported case of pa raneoplastic CP.