Prescription-event and other forms of epidemiological monitoring of side-effects in the UK

Authors
Dunn, N Mann, RD
Citation
N. Dunn et Rd. Mann, Prescription-event and other forms of epidemiological monitoring of side-effects in the UK, CLIN EXP AL, 29, 1999, pp. 217-239
Citations number
68
Categorie Soggetti
Clinical Immunolgy & Infectious Disease",Immunology
Journal title
CLINICAL AND EXPERIMENTAL ALLERGY
ISSN journal
09547894 → ACNP
Volume
29
Year of publication
1999
Supplement
3
Pages
217 - 239
Database
ISI
SICI code
0954-7894(199907)29:<217:PAOFOE>2.0.ZU;2-W
Abstract
The post-marketing surveillance (PMS) of drugs is necessary because of the limited size of the clinical safety database at the time of marketing. The principal hypothesis-generating methods of PMS are spontaneous reporting (e .g. the yellow card) and Prescription Event Monitoring. These methods are d iscussed in this chapter and certain basic pharmacoepidemiological issues t hat are relevant are briefly reviewed.