ENANTIOMER SEPARATION OF SELECTED ATROPISOMERIC POLYCHLORINATED-BIPHENYLS INCLUDING PCB-144 ON TERT.-BUTYLDIMETHYLSILYLATED BETA-CYCLODEXTRIN

The enantiomer separation of eight atropisomeric polychlorinated biphe nyls (PCBs) was studied by application of GC-MS and a chiral stationar y phase (CSP). The modified cyclodextrin consisted of 25% tert.-butyld imethylsilylated beta-cyclodextrin (beta-BSCD) in 15% diphenyl, 85% di methylpolysiloxane. The enantiomers of seven atropisomeric PCBs were a t least partly separated. Five of the separated enantiomers of PCB atr opisomers had a 2,3,4,6-substitution pattern on one phenyl ring. Empha sis was put on the atropisomer separation of PCB 144 (2,3,4,6,2',5'-he xachlorobiphenyl) which was not reported before on other CSPs. Several enantiomers of PCB atropisomers not separated on permethylated beta-c yclodextrin were separated on beta-BSCD. The efficiency of the PCB atr opisomer separation on beta-BSCD is complement to permethylated beta-c yclodextrin.