MRI OF THE BRAIN AND CRANIOCERVICAL JUNCTION IN MORQUIOS-DISEASE

We reviewed MRI of the brain and cervical spine in 11 patients with Mo rquio's disease. No abnormality was seen in the brain. The odontoid pe g was abnormal in all patients, with varying degrees of cord compressi on due to an anterior soft tissue mass and indentation by the posterio r arch of the atlas. The degree of cord compression was more marked th an suggested by the symptoms and signs. We recommend MRI of the cervic al spine in children with Morquio's disease before the development of neurological symptoms, to optimise the timing and type of surgical int ervention.