We describe an unusual case of acute liver injury that followed food-depend
ent exercise-induced anaphylaxis (FDEIAn). A 45-year-old man who experience
d anaphylactic shock induced by postprandial exercise and took alcohol that
night was admitted the following day to our hospital because of general fa
tigue. Laboratory examinations revealed elevated hepatic enzymes (aspartate
aminotransferase (AST) 6,110 IU, alanine aminotransferase (ALT) 4,178 IU),
He had two similar episodes in the past. We speculated that acute liver in
jury in this case might be induced by interaction of anaphylactic shock and
alcohol.