Background: Anaphylaxis is the most urgent clinical immunologic event. Effe
ctive treatment is best achieved by administration of epinephrine, Accident
al exposure to the responsible allergen is the most common cause of anaphyl
axis, and because it could be fatal within minutes, epinephrine in preloade
d syringes and auto-injectors has been introduced. In our experience patien
ts and medical personnel are not familiar with the use of this device.
Objective: We sought to assess community-based professionals' knowledge of
epinephrine auto-injector use and their ability to educate patients.
Methods: Study participants consisted of a medical convention's delegates a
nd emergency department personnel in metropolitan Toronto, as well as pharm
acists of the target hospitals and retail pharmacists, Research assistants
approached eligible professionals to fill out a questionnaire and demonstra
te their ability to use a standard placebo auto-injector trainer.
Results: A total of 122 professionals (composed of emergency physicians, fa
mily practitioners, and pediatricians) consented to participate in this stu
dy. The majority of participants (81%) did not have a placebo trainer to ed
ucate their patients; 76% did not know the 2 available dose strengths. To p
rovide instructions and reinforcement, physicians clearly must have the nec
essary skills and knowledge, Jet only 25% of the study participants were ab
le to demonstrate the 3 steps of injection correctly.
Conclusion: Our study highlights a specific and important deficiency in med
ical professionals' care of patients at risk for anaphylaxis. The results c
hallenge the current methods of educating professionals, as well as patient
s, when prescribing or using epinephrine auto-injectors. Clearly a new appr
oach to educating and maintaining such skills is required.