Efficient syntheses of methyl 2-amino-2-deoxy-3,4,6-tri-O-benzyl-alpha-D-glucopyranoside and its 2-tert-butoxycarbonylamino- and 2-methylamino derivatives from N-acetyl-D-glucosamine

The synthesis of the title compounds started with N-acetylglucosamine which was converted into the corresponding methyl glycoside and O-protected with benzyl groups. Subsequent N-protection as its N-BOC-N-acetyl derivative an d sequential removal of the N-acetyl group and of the BOC group led in good yield to the target compounds in multigram amounts.