Preparation and functionalization of an alkenylcopper reagent formed by the syn addition of (dialkoxyphosphinyl) difluoromethylcopper to hexafluoro-2-butyne

Authors
Guneratne, RD Burton, DJ
Citation
Rd. Guneratne et Dj. Burton, Preparation and functionalization of an alkenylcopper reagent formed by the syn addition of (dialkoxyphosphinyl) difluoromethylcopper to hexafluoro-2-butyne, J FLUORINE, 98(1), 1999, pp. 11-15
Citations number
19
Categorie Soggetti
Inorganic & Nuclear Chemistry
Journal title
JOURNAL OF FLUORINE CHEMISTRY
ISSN journal
00221139 → ACNP
Volume
98
Issue
1
Year of publication
1999
Pages
11 - 15
Database
ISI
SICI code
0022-1139(19990810)98:1<11:PAFOAA>2.0.ZU;2-#
Abstract
(Dialkoxyphosphinyl)difluoromethylcopper, readily prepared from dialkyl bro modifluoromethylphosphonate, undergoes facile, stereospecific, syn addition to hexafluoro-2-butyne, to form the cis alkenylcopper reagent in good yiel d. This intermediate can be functionalized with electrophiles, such as aryl , alkyl, and alkenyl halides. (C) 1999 Elsevier Science S.A. All rights res erved.