Alarmingly high occurrence and case fatality of acute coronary heart disease events in Estonia: results from the Tallinn AMI register 1991-94

Objective, The purpose of this study was to produce stable estimates for th e incidence, attack and mortality rates and case fatality of acute myocardi al infarction (AMI) in Tallinn, the capital of Estonia. Research design and methods, The Tallinn AMI register covers the population aged 25-64 years and official residents of Tallinn. The register follows t he WHO MONICA project protocols in the data collection and diagnostic evalu ation of suspected AMI events and CI-IB death, Results, Age-standardized annual incidence, attack rate and mortality in me n aged 35-64 years were high, varying from (per 100 000 per year) 352, 499 and 208, respectively, in 1991 to 438, 628 and 317, respectively, in 1993. In addition, in women, annual incidence, attack rate and mortality were hig h, varying from (per 100 000 per year) 82, 100 and 31, respectively, in 199 1 to 110 and 142 in 1993 for the incidence and attack rate, and to 61 in 19 92 for mortality. The percentage of out-of-hospital coronary death (sudden death) increased in men from 33 to 52% and in women from 24 to 42% during 1 991-94, and the 28-day case fatality increased in men from 42 to 58% and in women from 32 to 50%, In Tallinn, women with AMI were treated as actively as men with invasive treatment (thrombolysis, angioplasty, bypass surgery) during the acute phase of MI. Conclusions, The incidence, attack rate and mortality of AMI were high in b oth men and women in Tallinn, The high 28-day case fatality observed was pr imarily due to the high proportion of out-of-hospital deaths.