Benzylisoquinoline alkaloids from Gnetum parvifolium

Authors
Citation
Q. Xu et M. Lin, Benzylisoquinoline alkaloids from Gnetum parvifolium, J NAT PROD, 62(7), 1999, pp. 1025-1027
Citations number
22
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
01633864 → ACNP
Volume
62
Issue
7
Year of publication
1999
Pages
1025 - 1027
Database
ISI
SICI code
0163-3864(199907)62:7<1025:BAFGP>2.0.ZU;2-U
Abstract
The investigation of the chemical constituents from the lianas of Gnetum pa rvifolium resulted in the isolation of three new benzylisoquinoline alkaloi ds, (+/-)-N-methylhigenamine (1), (-)-N-methylhigenamine N-oxide (2), and ( +/-)-8-(p-hydroxybenzyl)-2,3,10,11-tetrahydroxyprotoberberine (3), together with two known alkaloids, higenamine and trigonelline. The structures of 1 -3 were determined by chemical methods and spectral analysis including 2D N MR and NOE studies.