Alkaloids from the roots of Goniothalamus griffithii

Three new alkaloids-griffithazanone A (1), griffithdione (2), and griffithi nam (3)-were isolated from the roots of Goniothalamus griffithii, along wit h six known compounds, 4-methyl-2,9, 10-(2H)-1-azaanthracenetrione (4), vel utinam, aristololactam BI, aristololactam BII, aristololactam AII, and norc epharanone B. Their structures were elucidated on the basis of spectral and chemical methods. The absolute configuration of griffithazanone A (1) was determined by the preparation of Mosher's esters.