Two new naturally occurring 1-aryl-2,3-naphthalide lignans, cilinaphthalide
A (1) and cilinaphthalide B (2), and nine known compounds were isolated fr
om the whole plant of Justicia ciliata. Their structures were established b
y spectral analysis, and their cytotoxic activity was evaluated against sev
eral different cell lines. The known compound, justicidin A, showed potent
cytotoxic effects against T-24, CaSki, SiHa, HT-3, PLC/PRF/5, and 212 cells
in vitro.