CHARACTERIZATION OF DNA-BINDING SITES FOR THE BVGA PROTEIN OF BORDETELLA-PERTUSSIS

Authors
KARIMOVA G ULLMANN A
Citation
G. Karimova et A. Ullmann, CHARACTERIZATION OF DNA-BINDING SITES FOR THE BVGA PROTEIN OF BORDETELLA-PERTUSSIS, Journal of bacteriology, 179(11), 1997, pp. 3790-3792
Citations number
21
Categorie Soggetti
Microbiology
Journal title
Journal of bacteriology → ACNP
ISSN journal
00219193
Volume
179
Issue
11
Year of publication
1997
Pages
3790 - 3792
Database
ISI
SICI code
0021-9193(1997)179:11<3790:CODSFT>2.0.ZU;2-S
Abstract
Expression of virulence-associated genes in Bordetella pertussis is un der the control of the pleiotropic regulator BvgA. Although previous s tudies have identified recognition sequences for BvgA in several promo ter regions, their structures have not been clearly characterized. We show that the BvgA binding sites within the bvgp(1) and cyaA promoters consist of inverted repeats and suggest that inverted-repeat motifs m ay represent the recognition elements for DNA-BvgA interaction.