There have been few clinical reports of successful replantation assisted wi
th hyperbaric oxygen (HBO) therapy. In order to improve replant survival, t
he author has used HBO in ten digital replantations of crush, avulsion, and
degloving amputations. Seven of ten replants survived and the other three
failed. The failed three digits demonstrated remarkable color changes durin
g HBO therapy. No color changes were observed in six of the seven surviving
digits under HBO. The remaining digit showed a slight color difference bet
ween pre- and post-therapy. It appears that hyperbaric oxygen is potentiall
y effective in distinguishing "uneventful" replants in which color does not
change during HBO therapy, while hyperbaric oxygen could not salvage those
"congestion to necrosis" replants in which the color became bright ver-mil
ion under hyperbaric oxygen therapy. The difference in digital color reacti
on to hyperbaric oxygen may be helpful in early decisions to employ salvagi
ng procedures.