A late onset of cerebellar degeneration was diagnosed in a one-and-a-half-y
ear-old Siamese cat. The animal had been presented with mild ataxia involvi
ng all four limbs. Over the following two years, the signs gradually progre
ssed to severe incoordination, a frequent tendency to fall and a head tremo
r. The neurological signs were consistent with a diffuse cerebellar lesion
and the cat was euthanased. Profound and diffuse Purkinje cell loss was fou
nd on histopathological examination, but no aetiological agent was detected
.