Low-grade B-cell lymphoma of mucosa-associated lymphoid tissue in the lung: a report of a case with pleural dissemination

A 79-year-old man with an abnormal shadow on a chest radiograph was referre d to our hospital for further examination. Open lung biopsy revealed numero us nodules on visceral pleura and the tumor, obtained by wedge resection of the left upper lobe of the lung, consisted of centrocyte-like cells and ly mphoplasmacytoid cells, expressing CD20 and CD79a. These tells invaded bron chiolar epithelium to form lymphoepithelial lesions. The pleural-based nodu les were similarly composed of the same cells as those in the left upper lo be tumor. To our knowledge, pleural dissemination of low grade B-cell lymph oma of mucosa-associated lymphoid tissue has not been reported previously. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.