Atomic absorption spectrophotometry was used to detect lenticular nickel, c
hromium, manganese, iron and aluminum levels in 37 senile cataractous and 9
normal human lenses. The nuclear parts of the lenses were used for the stu
dy in both groups. It was found that the concentrations of nickel and iron
were significantly higher, and those of chromium, manganese and aluminum we
re significantly lower in human cataractous lenses than those in normal hum
an lenses. None of the elements showed a significant difference according t
o sex in both groups. As remarkable differences in chromium, manganese, iro
n, aluminum and nickel levels exist in cataractous lenses, all the five ele
ments may play some roles in cataractogenesis.