Cardiac transplantation is now a well-accepted therapy for patients with ad
vanced heart failure. In appropriately selected recipients, it has shown to
significantly improve the survival and quality of life. The shortage of ap
propiate cardiac donor hearts, the costs of cardiac transplantation and its
associated long-term medical follow-up, and the potential morbidity and mo
rtality associated with the procedure and with life after transplantation m
andates the judicious application of cardiac transplantation to appropiate
recipients. A review of current indications, contraindications and evaluati
on of patients for cardiac transplantation is presented.