Streptococcal bacteremia is an uncommon presentation for colorectal maligna
ncy, yet most physicians are aware of the association between Streptococcus
bovis infection and these malignancies. Many are unaware, however, that ot
her streptococcal species are associated with colon and rectal cancers. In
this case report and brief review, we highlight this association and discus
s a case of Streptococcus sanguis bacteremia associated with an early invas
ive rectal cancer.