A straightforward synthesis of 1,2-dihydronaphtho[2,1-b]furans from 2-naphthols

Authors
Arrault, A Touzeau, F Guillaumet, G Merour, JY
Citation
A. Arrault et al., A straightforward synthesis of 1,2-dihydronaphtho[2,1-b]furans from 2-naphthols, SYNTHESIS-S, (7), 1999, pp. 1241-1245
Citations number
31
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
SYNTHESIS-STUTTGART
ISSN journal
00397881 → ACNP
Issue
7
Year of publication
1999
Pages
1241 - 1245
Database
ISI
SICI code
0039-7881(199907):7<1241:ASSO1F>2.0.ZU;2-2
Abstract
A one-step synthesis of ethyl 1,2-dihydronaphtho[2,1-b]furan-2-carboxylates 2a-g from substituted 2-naphthols and ethyl 2,3-dibromopropanoate is descr ibed. 3,4-Dibromobutan-2-one and 2-chloroacrylonitrile react with 2-naphtho l (1a) to afford the corresponding 2-cyano- or 2-acetylnaphtho[2,1-b]furans 6 and 7, respectively.