Highly stereoselective induction in the cobalt-mediated [2+2+2] cycloaddition of chiral phosphine oxides substituted linear enediynes

Authors
Slowinski, F Aubert, C Malacria, M
Citation
F. Slowinski et al., Highly stereoselective induction in the cobalt-mediated [2+2+2] cycloaddition of chiral phosphine oxides substituted linear enediynes, TETRAHEDR L, 40(32), 1999, pp. 5849-5852
Citations number
29
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
32
Year of publication
1999
Pages
5849 - 5852
Database
ISI
SICI code
0040-4039(19990806)40:32<5849:HSIITC>2.0.ZU;2-R
Abstract
The cobalt(I)-catalyzed highly stereoselective [2+2+2] cyclization has been realized for the first time with chiral phosphine oxides substituted linea r enediynes. Depending the substituents on the phosphorus atom, the cycload dition was achieved with a level of diastereoselectivity of 74%. (C) 1999 E lsevier Science Ltd. All rights reserved.