Resolution of inherently chiral resorcarene derivatives by enantioselective HPLC

Authors
Bohmer, V Caccamese, S Principato, G Schmidt, C
Citation
V. Bohmer et al., Resolution of inherently chiral resorcarene derivatives by enantioselective HPLC, TETRAHEDR L, 40(32), 1999, pp. 5927-5930
Citations number
14
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
32
Year of publication
1999
Pages
5927 - 5930
Database
ISI
SICI code
0040-4039(19990806)40:32<5927:ROICRD>2.0.ZU;2-G
Abstract
The HPLC enantiomeric resolution of five inherently chiral tetrabenzoxazine derivatives of resorcarenes has been achieved by HPLC using Whelk-Ol and i n one case Chiralpak AD as stationary phases. Enantiomeric separation was o nly observed in a very narrow range of mobile phase compositions. On-column enantiomeric interconversion of a;racemic compound with a typical plateau- like elution profile was observed using a Chiralpak AO column (C) 1999 Publ ished by Elsevier Science Ltd. Atl rights reserved.