Intraoperative extracorporeal irradiation and replantation (IEIR) in the treatment of primary malignant bone tumors

In 6 patients with primary malignant bone tumors (4 Ewing, 1 recurrent Adam antinoma, 3 maligne Haemangioperizytoma) the local therapy was performed as intraoperative extracorporeal irradiation and replantation. During the fol low-up 10 (6-24) months no local recurrence in the replanted segment occurr ed. One recurrence occurred in the host bed; in two cases the replanted seg ment had to be removed because of severe infection. The other cases showed good functional and radiological results. These clinical findings and the r eports in the literature seem to allow the application of the intraoperativ e extracorporeal irradiation and replantation procedure for defect reconstr uction in cases of chemo- and radiotherapy-sensitive hone tumors.