Bromfenac(Duract)-associated hepatic failure requiring liver transplantation

Authors
Hunter, EB Johnston, PE Tanner, G Pinson, CW Awad, JA
Citation
Eb. Hunter et al., Bromfenac(Duract)-associated hepatic failure requiring liver transplantation, AM J GASTRO, 94(8), 1999, pp. 2299-2301
Citations number
4
Categorie Soggetti
Gastroenerology and Hepatology
Journal title
AMERICAN JOURNAL OF GASTROENTEROLOGY
ISSN journal
00029270 → ACNP
Volume
94
Issue
8
Year of publication
1999
Pages
2299 - 2301
Database
ISI
SICI code
0002-9270(199908)94:8<2299:BHFRLT>2.0.ZU;2-Z
Abstract
Bromfenac sodium (Duract) is a phenylacetic acid-derived nonsteroidal anti- inflammatory agent introduced in the United States in 1997 and withdrawn in 1998. We describe the first case of fulminant hepatic failure associated w ith this agent treated successfully with liver transplantation. Similaritie s to hepatotoxicity with related agents is discussed. (Am J Gastroenterol 1 999;94:2299-2301. (C) 1999 by Am. Coll. of Gastroenterology).