The threat of exposure to chemical warfare agents has traditionally been co
nsidered a military issue. Several recent events have demonstrated that civ
ilians may also be exposed to these agents. The intentional or unintentiona
l release of a chemical warfare agent in a civilian community has the poten
tial to create thousands of casualties, thereby overwhelming local health a
nd medical resources. The resources of US communities to respond to chemica
l incidents have been designed primarily for industrial agents, but must be
expanded and developed regarding incident management, agent detection, pro
tection of emergency personnel, and clinical care. We present an overview o
f the risk that chemical warfare agents presently pose to civilian populati
ons and a discussion of the emergency medical and emergency public health i
ssues related to preparedness and response.