TEM-24 produced by four different species of Enterobacteriaceae, includingProvidencia rettgeri, in a single patient

Authors
Marchandin, H Carriere, C Sirot, D Jean-Pierre, H Darbas, H
Citation
H. Marchandin et al., TEM-24 produced by four different species of Enterobacteriaceae, includingProvidencia rettgeri, in a single patient, ANTIM AG CH, 43(8), 1999, pp. 2069-2073
Citations number
21
Categorie Soggetti
Microbiology
Journal title
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
ISSN journal
00664804 → ACNP
Volume
43
Issue
8
Year of publication
1999
Pages
2069 - 2073
Database
ISI
SICI code
0066-4804(199908)43:8<2069:TPBFDS>2.0.ZU;2-N
Abstract
Four species of members of the family Enterobacteriaceae harboring extended -spectrum beta-lactamase (ESBL) were recovered in a single patient hospital ized in an intensive care unit. Among these isolates, we describe for the f irst time an ESBL-producing Providencia rettgeri strain. Bacteria from the same species were shown to be genetically related by pulsed-field gel elect rophoresis analysis. These strains produced the same TEM derivative ESBL, c haracterized as TEM-24. This enzyme had the peculiarity of being encoded by a large conjugative plasmid of 180 kb, never previously described for such an ESBL.