Absorbed doses to patients from Pt-191-;Pt-193m- and Pt-195m-cisplatin

Authors
Areberg, J Norrgren, K Mattsson, S
Citation
J. Areberg et al., Absorbed doses to patients from Pt-191-;Pt-193m- and Pt-195m-cisplatin, APPL RAD IS, 51(5), 1999, pp. 581-586
Citations number
34
Categorie Soggetti
Multidisciplinary
Journal title
APPLIED RADIATION AND ISOTOPES
ISSN journal
09698043 → ACNP
Volume
51
Issue
5
Year of publication
1999
Pages
581 - 586
Database
ISI
SICI code
0969-8043(199911)51:5<581:ADTPFP>2.0.ZU;2-B
Abstract
Cisplatin, a chemotherapeutic drug, can be synthesized using radioactive pl atinum and then used for pharmacokinetic studies and tumor imaging. We have calculated the absorbed doses to various organs and tissues as well as the effective doses from Pt-191-, Pt-193m- and Pt-195m-cisplatin after adminis tration to humans for diagnostic purposes. Liver was the organ that receive d the highest absorbed dose. The effective dose from Pt-191-, Pt-193m- and Pt-195m-cisplatin was 0.10 +/- 0.02, 0.17 +/- 0.04 and 0.23 +/- 0.05 mSv/MB q respectively. (C) 1999 Elsevier Science Ltd. All rights reserved.