When starting the experiments on foot and mouth disease on the Isle of Riem
s in October 1910, Friedrich Loeffler could continue investigations that ha
d been interrupted in 1907 by ministerial order. Loeffler's appointment to
Berlin in 1913 and his sudden death in 1915 lead to the temporary cessation
of work on the Riems. With high personal creativity and many years of semi
nal influence, Otto Waldmann carried Loeffler's ideas further, in the selec
tion of themes and research strategy, making the Riems a world famous place
of research. Some essential elements have determined life and research on
the island for decades: the development of measures against epidemics, the
conception of their application, the extension of research to new diseases
of economic significance, the close contacts with the veterinary practice a
t all times, the presentation of results to experts and the stimulating dis
cussions in the laboratory. I will try to briefly draw a bow covering the d
ecades of different social conditions to the present and to suggest that Lo
effler's ideas, which have been improved with the years, can affect many a
current decision, even though differentiated individually.